Location History:
- Durham, NC (US) (1997)
- Chapel Hill, NC (US) (1995 - 2003)
Company Filing History:
4 out of 78 
2 out of 1,270 
1 out of 1,215 
Years Active: 1995-2003
Title: The Innovative Mind of Oliver Smithies
Introduction
Oliver Smithies, an esteemed inventor based in Chapel Hill, NC, has made significant contributions to the field of genetics and biotechnology. With a remarkable portfolio of 6 patents, he has pioneered techniques that have advanced our understanding of genetic engineering and therapeutic applications.
Latest Patents
Among his latest patents, Oliver has developed methods for homologous recombination to create universal donor cells and chimeric mammalian hosts. These innovations involve inactivating genes associated with MHC (Major Histocompatibility Complex) antigens, specifically the β-microglobulin gene. By doing so, the resulting cells can potentially serve as universal donor cells. Moreover, his work includes modifying embryonic stem cells through homologous recombination, which may lead to the production of chimeric or transgenic mammalian hosts. These hosts are envisioned as sources for universal donor organs or as models for further drug and transplantation therapies. Additionally, his patents describe methods for homologous recombination in non-transformed mammalian somatic cells.
Career Highlights
Oliver Smithies has had a distinguished career, having worked with notable organizations such as Cell Genesys, Inc. and the University of North Carolina at Chapel Hill. Through his work at these institutions, he has helped push the boundaries of genetic research and therapeutic possibilities.
Collaborations
Throughout his career, Oliver has collaborated with accomplished professionals, including Beverly H. Koller and Raju S. Kucherlapati. These partnerships have enriched his research endeavors and contributed to groundbreaking advancements in biotechnology.
Conclusion
Oliver Smithies is a pivotal figure in the realm of genetic engineering. His innovations, particularly in the area of homologous recombination, promise to unlock new potentials in medical science. With a legacy of patents and collaborations, he continues to inspire future generations of inventors and researchers, driving the field forward.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.