Olga Dedova

Title: Olga Dedova: Innovator in Peptide Therapeutics

Introduction

Olga Dedova is a prominent inventor based in Highland Park, NJ (US). She has made significant contributions to the field of peptide therapeutics, holding 2 patents that focus on insulin and insulin-like growth factor receptors.

Latest Patents

Her latest patents include innovations related to insulin and IGF-1 receptor agonists and antagonists. These patents disclose peptide sequences capable of binding to insulin and/or insulin-like growth factor receptors with either agonist or antagonist activity. The invention identifies at least two different binding sites present on these receptors, which selectively bind the peptides. As agonists, these peptides may be useful for developing therapeutics to supplement or replace endogenous peptide hormones. Additionally, the antagonist peptides may also be developed as therapeutics. Another significant patent involves a modified phage display method for detecting and identifying target binders. This method transforms host cells with two separate phages and selects to eliminate non-paired targets and binders. The invention also relates to antibodies that bind to complexes of target and target binders, nucleic acids encoding these peptides, and their use in diagnostics and therapeutics.

Career Highlights

Olga has worked with notable companies such as Antyra Inc. and Novo Nordisk A/S. Her work has significantly impacted the development of peptide-based therapeutics and diagnostics.

Collaborations

Some of her coworkers include Renuka Pillutla and Arthur J. Blume. Their collaborative efforts have contributed to advancing research in the field of peptide therapeutics.

Conclusion

Olga Dedova's innovative work in peptide therapeutics and her contributions to the scientific community highlight her as a key figure in the field. Her patents and collaborations continue to pave the way for advancements in medical therapeutics.