Company Filing History:
7 out of 114 
1 out of 2 
1 out of 1 Years Active: 1979-1991
Title: Nobuya Ohtomo: Innovator in Recombinant DNA Technology
Introduction
Nobuya Ohtomo is a prominent inventor based in Kumamoto, Japan. He has made significant contributions to the field of biotechnology, particularly in the development of recombinant DNA technologies. With a total of 9 patents, Ohtomo's work has paved the way for advancements in vaccine production and diagnostic reagents.
Latest Patents
Ohtomo's latest patents include a novel recombinant plasmid inserted with a herpes simplex virus gene. This plasmid vector contains a yeast DNA sequence and an Escherichia coli DNA sequence, carrying a promoter region and a herpes simplex virus gN gene (HSVgB). The HSVgB gene is modified to lack an N-terminal portion, making it useful for producing transformed yeast that can generate HSVgB proteins suitable for vaccines and diagnostic reagents for herpes simplex virus infections. Another significant patent involves recombinant DNA inserted with hepatitis B virus genes. This DNA comprises three fragments of Hepatitis B virus DNA recombined with a vector that allows for the production of HBV proteins, which have the same immunological properties as natural HBV proteins. These proteins can be utilized for the preparation of HBV vaccines and diagnostic reagents.
Career Highlights
Throughout his career, Ohtomo has worked with notable organizations, including the Chemo-Sero-Therapeutic Research Institute and The Juridical Foundation. His innovative research has contributed to the understanding and treatment of viral infections, particularly in the context of vaccine development.
Collaborations
Ohtomo has collaborated with esteemed colleagues such as Fukusaburo Hamada and Chikateru Nozaki. These partnerships have further enhanced his research and development efforts in the field of biotechnology.
Conclusion
Nobuya Ohtomo's contributions to recombinant DNA technology have had a lasting impact on the fields of vaccine development and diagnostics. His innovative patents and collaborations continue to influence advancements in biotechnology.