The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 24, 1979

Filed:

Sep. 28, 1978
Applicant:
Inventors:

Kyosuke Mizuno, Kumamoto, JP;

Atsushi Miyanohara, Kumamoto, JP;

Yoshimitsu Ishihara, Kumamoto, JP;

Nobuya Ohtomo, Kumamoto, JP;

Assignee:

Juridical Foundation, Kumamoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
435239 ; 424 89 ;
Abstract

An improved method for purification of HBs antigen comprising passing a partially purified HBs antigen prepared from blood plasma or serum through a column filled with an anion exchanger which may be equilibrated with a buffer solution having a specific ionic strength and pH level, and further passing the resulting effluent through a column filled with a cation exchanger which may be equilibrated with a buffer solution having a specific ionic strength and pH level. The HBs antigen obtained by the present invention is highly purified and is useful for preparing vaccine for preventing Viral Hepatitis Type B.


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