The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 1986
Filed:
Oct. 01, 1984
Applicant:
Inventors:
Keishin Sugahara, Kumamoto, JP;
Chikateru Nozaki, Kumamoto, JP;
Fukusaburo Hamada, Kumamoto, JP;
Fumio Miake, Kumamoto, JP;
Nobuya Ohtomo, Kumamoto, JP;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; A61K / ;
U.S. Cl.
CPC ...
435 68 ; 424 88 ; 424 89 ; 530403 ; 530404 ; 530406 ;
Abstract
A method for purification of HBs antigen, which comprises treating an HBs tigen-containing material with an acid, optionally subjecting to salting out with ammonium sulfate, and subjecting the material to a chromatography with hydroxyapatite, by which a highly purified HBs antigen suitable for the preparation of HBV vaccine or diagnostic agent can be obtained in an industrial scale. This method is particularly useful for the purification of HBs antigen-containing material produced by recombinants obtained by DNA recombination technique.