Location History:
- Bengaluru, IN (2011)
- Karnataka, IN (2014)
Company Filing History:
Years Active: 2011-2014
Title: Nita Roy: Innovator in Biopharmaceuticals
Introduction
Nita Roy is a prominent inventor based in Karnataka, India, known for her significant contributions to the field of biopharmaceuticals. With a focus on protein purification and insulin conjugates, she has made strides in developing innovative methods that enhance the efficacy of therapeutic proteins.
Latest Patents
Nita Roy holds two notable patents. The first patent is titled "Method of obtaining a purified, biologically active heterologous protein." This invention relates to methods of separation and purification of impurities, yielding a purified heterologous protein product that is devoid of related impurities or contains minimal quantities of glycosylated impurities. Specifically, it addresses the identification of glycosylated forms of insulin analogues, such as glargine impurities, characterized post-expression in yeast-based systems. The invention also encompasses methods for cloning the gene encoding the protein insulin glargine, inserting the gene into a suitable yeast host, and producing cultures of the recombinant strain, which stimulates expression, secretion, and purification of the heterologous polypeptide post-fermentation.
The second patent is for a "Process for the preparation of insulin conjugate IN-105." This invention claims a process for creating an insulin-oligomer conjugate, IN-105. The IN-105 precursor, characterized by the formula G-A-V-R-[B-Chain]-R-D-A-D-D-R-[A-Chain], is cloned and expressed. The biosynthetic precursor is then conjugated with an activated oligomer, and the resulting IN-105 precursor-oligomer conjugate is treated with protease and purified to yield an active insulin-oligomer conjugate.
Career Highlights
Nita Roy is currently employed at Biocon Limited, a leading biopharmaceutical company in India. Her work at Biocon has allowed her to contribute to the development of innovative biopharmaceutical products that address critical health challenges.
Collaborations
Nita collaborates with talented professionals in her field, including Partha Hazra and Nitesh Dave. Their combined expertise fosters a collaborative environment that drives innovation and research in biopharmaceuticals.
Conclusion
Nita Roy's contributions to the field of biopharmaceuticals through her patents and work at Biocon Limited highlight her role as a key innovator. Her advancements in protein purification and
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