The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 15, 2011
Filed:
Oct. 13, 2005
Nitesh Dave, Bangalore, IN;
Partha Hazra, Bangalore, IN;
Anuj Goel, Bangalore, IN;
Nita Roy, Bangalore, IN;
Anand Khedkar, Bangalore, IN;
Harish Iyer, Bangalore, IN;
Gautam Krishnan, Bangalore, IN;
H. S. Manjunath, Bangalore, IN;
Shrikumar Suryanarayan, Bangalore, IN;
Govindasamy Manikam, Bangalore, IN;
Goldy Sachdev, Bangalore, IN;
Mayank Garg, Bangalore, IN;
Nitesh Dave, Bangalore, IN;
Partha Hazra, Bangalore, IN;
Anuj Goel, Bangalore, IN;
Nita Roy, Bangalore, IN;
Anand Khedkar, Bangalore, IN;
Harish Iyer, Bangalore, IN;
Gautam Krishnan, Bangalore, IN;
H. S. Manjunath, Bangalore, IN;
Shrikumar Suryanarayan, Bangalore, IN;
Govindasamy Manikam, Bangalore, IN;
Goldy Sachdev, Bangalore, IN;
Mayank Garg, Bangalore, IN;
Biocon Limited, , IN;
Abstract
The invention claims a process for making an insulin-oligomer conjugate IN-105. IN-105 precursor having formula G-A-V-R-[B-Chain]-R-D-A-D-D-R-[A-Chain] is cloned and expressed in. The biosynthetic precursor is then conjugated with an activated oligomer. The IN-105 precursor-oligomer conjugate is then treated with protease and purified to afford active insulin-oligomer conjugate of formula insulin-OC—CH—CH—(OCHCH)—OCH.