Århus, Denmark

Niels Jonas Heilskov Graversen


 

Average Co-Inventor Count = 5.9

ph-index = 2

Forward Citations = 27(Granted Patents)


Location History:

  • Arhus, DK (2010)
  • Åbyhøj, DK (2011)
  • Århus, DK (2012)

Company Filing History:


Years Active: 2010-2012

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4 patents (USPTO):

Title: Niels Jonas Heilskov Graversen: Innovator in Polypeptide Design

Introduction

Niels Jonas Heilskov Graversen is a notable inventor based in Århus, Denmark. He has made significant contributions to the field of biotechnology, particularly in the design of trimeric polypeptides. With a total of 4 patents to his name, Graversen's work has implications for various therapeutic and diagnostic applications.

Latest Patents

One of Graversen's latest patents is focused on a trimerising module. This invention relates to the design of trimeric polypeptides using structural elements derived from the tetranectin protein family. The application of these multi-functional molecules extends to protein library technology, including phage display technology, as well as diagnostic and therapeutic systems such as human gene therapy and imaging. The trimeric polypeptides are constructed as monomer polypeptide constructs that include at least one tetranectin trimerising structural element (TTSE), which is covalently linked to at least one heterologous moiety. This TTSE is capable of forming a stable complex with two other TTSEs, or as an oligomer comprised of two monomer polypeptide constructs.

Career Highlights

Throughout his career, Graversen has worked with prominent companies in the biotechnology sector, including Anaphore, Inc. and Hoffmann-La Roche Inc. His innovative approach to polypeptide design has positioned him as a key figure in the development of new therapeutic solutions.

Collaborations

Graversen has collaborated with notable professionals in his field, including Michael Etzerodt and Thor Las Holtet. These collaborations have further enhanced his research and development efforts.

Conclusion

Niels Jonas Heilskov Graversen's contributions to the field of biotechnology through his innovative designs of trimeric polypeptides demonstrate his commitment to advancing therapeutic and diagnostic technologies. His work continues to influence the landscape of protein engineering and molecular design.

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