This inventor holds 3 USPTO granted patents. Top assignees: E. R. Squibb Sons, Inc., Other. Active years: 1988-1989.
Location History:
- Merseyside, GB (1988)
- Wirral, GB (1989)
- Fareham, Hants, PO16 9TA, GB (1989)
Company Filing History:

Years Active: 1988-1989
Title: Innovations of Nicholas I Payne
Introduction
Nicholas I Payne is a notable inventor based in Merseyside, GB. He has made significant contributions to the field of pharmaceutical formulations, holding a total of 3 patents. His work focuses on enhancing the stability and effectiveness of various medicinal products.
Latest Patents
One of his latest patents is a steroid cream formulation that boasts enhanced physical and chemical stability. This formulation includes a specific compound, (11.beta.,17.alpha.)-17-(ethylthio)-9.alpha.-fluoro-11.beta.-hydroxy-17-(methylthio)androsta-1,4-dien-3-one (tipredane), combined with a vehicle primarily made of propylene glycol and water. The formulation also incorporates a sodium citrate or potassium citrate buffer to achieve an acid value greater than 3, along with a high melting point wax to ensure proper consistency without compromising the stability of the tipredane. Additionally, it contains benzyl alcohol as a preservative and various emulsifiers and emollients.
Another significant patent involves a spray-drying method for preparing liposomes and the products produced by this method. This innovative approach allows for the creation of a stable liposome precursor, which can be stored dry and reconstituted with water just before use. The dry liposome precursor is a valuable advancement in the preparation of liposomal formulations.
Career Highlights
Throughout his career, Nicholas I Payne has worked with reputable companies, including E. R. Squibb Sons, Inc. His experience in the pharmaceutical industry has enabled him to develop groundbreaking formulations that enhance the efficacy of medicinal products.
Collaborations
Nicholas has collaborated with notable professionals in his field, including Cheryl V Ambrose and J Roger Salmon. These collaborations have contributed to the advancement of his innovative work.
Conclusion
Nicholas I Payne's contributions to pharmaceutical innovations demonstrate his commitment to improving medicinal formulations. His patents reflect a deep understanding of chemical stability and formulation techniques, making him a significant figure in the field.