The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 1989

Filed:

Jan. 17, 1989
Applicant:
Inventors:

Peter Timmins, Irby, Wirral, Merseyside, L61 4YP, GB;

Nicholas I Payne, Fareham, Hants, PO16 9TA, GB;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
514169 ; 514179 ; 514252 ; 514399 ;
Abstract

A steroid cream formulation which has enhanced physical and chemical stability is formed of (11.beta.,17.alpha.)-17-(ethylthio)-9.alpha.-fluoro-11.beta.-hydroxy-17-(m ethylthio)androsta-1,4-dien-3-one (tipredane), and a vehicle containing as major ingredients propylene glycol and water together with a sodium citrate or potassium citrate buffer to impart an acid value to the cream formulation of greater than 3, a high melting point wax, such as white wax, to impart proper consistency without adversely affecting stability of the tipredane, benzyl alcohol as a preservative, together with one or more emulsifiers, which include glyceryl stearate, one or more emollients which include isopropyl isostearate or isopropyl palmitate, lubricants and other conventional cream formulation ingredients.


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