Los Angeles, CA, United States of America

Neil A O'Brien

USPTO Granted Patents = 6 

 

Average Co-Inventor Count = 4.4

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2023-2025

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6 patents (USPTO):

Title: **Innovator Spotlight: Neil A. O'Brien - Pioneering Cancer Therapy Innovations**

Introduction

Neil A. O'Brien is an accomplished inventor based in Los Angeles, CA, who has made significant contributions to the field of cancer therapeutics. With a total of two patents to his name, O'Brien is at the forefront of developing innovative antigen-binding proteins that target specific cancer-related proteins, offering new hope for patients.

Latest Patents

O'Brien's latest patents include groundbreaking work on Claudin-6 antibodies and drug conjugates, which are designed to bind to Extracellular Loop 2 (EL2) of the extracellular domain of Claudin-6 (CLDN6). This patent discloses various related polypeptides, nucleic acids, vectors, and pharmaceutical compositions that may significantly enhance cancer treatment methodologies.

In addition, he has also patented Claudin-18 antibodies and methods of treating cancer. This invention covers bispecific antigen-binding proteins targeting Claudin-18.2, generating novel conjugates that can improve treatment efficiency. By focusing on Extracellular Loop 1 (EL1) of CLDN18.2, O'Brien's patents provide a broader spectrum of tools to combat cancer, including kits and methods for treating patients.

Career Highlights

Neil A. O'Brien currently works at the University of California, where he combines his expertise in antibody engineering with cutting-edge research in oncology. His innovative approaches in the laboratory have positioned him as a key player in the development of advanced cancer therapies.

Collaborations

O'Brien collaborates with talented coworkers such as Dylan Conklin and Martina S. McDermott, both of whom contribute to the multidisciplinary efforts in researching and developing novel drug conjugates and treatments for cancer. Together, they leverage their collective expertise to further enhance the outcomes of their innovative projects.

Conclusion

With a focus on specific antigen-targeting approaches, Neil A. O'Brien exemplifies dedication to innovation in the field of cancer therapeutics. His patents represent a crucial advancement in treatment options and demonstrate the potential of antibody-based therapies. As he continues to work at the University of California, O'Brien's contributions promise to pave the way for new hopes in oncology.

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