The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 2026
Filed:
Mar. 25, 2020
California Institute of Technology, Pasadena, CA (US);
1200 Pharma Llc, Culver City, CA (US);
The Regents of the University of California, Oakland, CA (US);
Brendan M. O'boyle, Monrovia, CA (US);
Corey M. Reeves, San Mateo, CA (US);
Justin A. Hilf, Los Angeles, CA (US);
Brian M. Stoltz, San Marino, CA (US);
Michael D. Bartberger, Sherman Oaks, CA (US);
Steven J. Wittenberger, Sherman Oaks, CA (US);
Oliver C. Loson, Culver City, CA (US);
Martina S. Mcdermott, Los Angeles, CA (US);
Neil A. O'brien, Los Angeles, CA (US);
Dennis Slamon, Los Angeles, CA (US);
California Institute of Technology, Pasadena, CA (US);
1200 Pharma LLC, Culver City, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The present disclosure describes compounds of formulas (I)-(V) and methods of making the same. The compounds of the present disclosure are useful as inhibitors of PRMT5 activity and in methods of treating cancers and other diseases.