The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2025

Filed:

Nov. 15, 2019
Applicants:

California Institute of Technology, Pasadena, CA (US);

1200 Pharma Llc, Culver City, CA (US);

The Regents of the University of California, Oakland, CA (US);

Inventors:

Corey M. Reeves, San Mateo, CA (US);

Brendan M. O'boyle, Monrovia, CA (US);

Justin A. Hilf, Culver City, CA (US);

Dylan Conklin, Los Angeles, CA (US);

Martina S. Mcdermott, Los Angeles, CA (US);

Neil A. O'brien, Los Angeles, CA (US);

Michael J. Palazzolo, Los Angeles, CA (US);

Dennis Slamon, Los Angeles, CA (US);

Steven J. Wittenberger, Sherman Oaks, CA (US);

Oliver C. Loson, Monrovia, CA (US);

Michael D. Bartberger, Sherman Oaks, CA (US);

Brian M. Stoltz, San Marino, CA (US);

Assignees:

California Institute of Technology, Pasadena, CA (US);

1200 Pharma LLC, Culver City, CA (US);

The Regents of the University of California, Oakland, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); C07D 519/00 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07D 519/00 (2013.01); C12N 9/1205 (2013.01);
Abstract

The present disclosure provides compounds and compositions that are inhibitors of ERK1, ERK2, or both, and methods of use thereof.


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