Ned Scott Wingreen

Title: The Innovations of Ned Scott Wingreen

Introduction

Ned Scott Wingreen is a notable inventor based in Princeton, NJ, with a significant contribution to the field of biotechnology and laser technology. He holds a total of four patents, showcasing his innovative spirit and dedication to advancing scientific knowledge.

Latest Patents

One of Wingreen's latest patents focuses on small RNAs and bacterial strains involved in quorum sensing. This invention addresses how quorum-sensing bacteria communicate through extracellular signal molecules known as autoinducers, facilitating community-wide synchronization of gene expression. The patent identifies the protein Hfq as a mediator in the interactions between small regulatory RNAs (sRNAs) and specific messenger RNA (mRNA) targets. It provides nucleic acids encoding these sRNAs, strains with various deletions and mutations of qrr genes, and methods for identifying quorum-sensing regulators. Additionally, it includes an isolated Hfq protein and its conservative amino acid substitutions, along with nucleic acids encoding those proteins, recombinant methods for producing them, and antibodies against these proteins.

Another significant patent is for a quantum-dot cascade laser, which eliminates undesirable single phonon decays associated with quantum-well devices. This innovation achieves the elimination of single phonon decays through three-dimensional confinement, resulting in a substantial reduction in the threshold current. The patent details the use of vertical radiative transitions within single quantum dots contained by Bragg reflectors, along with specifications for dot size, dot density, and dot uniformity.

Career Highlights

Wingreen has had a distinguished career, working with prominent organizations such as NEC Research Institute, Inc. and Princeton University. His work has significantly impacted the fields of molecular biology and photonics, demonstrating his versatility and expertise.

Collaborations

Throughout his career, Wingreen has collaborated with esteemed colleagues, including Stuart A. Solin and Charles A. Stafford. These partnerships have contributed to the advancement of his research and innovations.

Conclusion

Ned Scott Wingreen's contributions to science through his patents and collaborations highlight his role as a leading inventor in biotechnology and laser technology. His work continues to influence various fields, showcasing the importance of innovation in scientific progress.