Natasha Barascuk

Title: Innovations by Natasha Barascuk: Pioneering Pathology and Cardiovascular Disease Diagnostics

Introduction

Natasha Barascuk is a prominent inventor based in Copenhagen, Denmark. She has made significant contributions to the field of diagnostics, particularly in the areas of pathology and cardiovascular disease. With a total of 3 patents, her work is at the forefront of medical innovation.

Latest Patents

One of her latest patents is focused on a pathology biomarker assay. This method of diagnosis involves conducting an immunoassay to measure neo-epitope containing protein fragments that are naturally present in biofluid samples. The process associates an elevation of the measured levels in patients above normal levels with the presence or extent of pathology. The immunoassay method includes contacting protein fragments in the sample with an immunological binding partner that reacts with a neo-epitope formed by protein cleavage. The extent of binding is then measured to assess the presence of these protein fragments. The neo-epitopes described in her patent include those from collagen types I, III, IV, V, VI, elastin, biglycan, decorin, lumican, versican, C-reactive protein, ApoE, and laminins.

Another significant patent by Barascuk involves biochemical markers for cardiovascular disease risk assessment. This method quantifies peptide fragments that comprise a neo-epitope formed by the cleavage of proteins found in atherosclerotic plaques. The assay involves contacting a sample, such as urine or serum, with an antibody that is reactive with the neo-epitope. The level of binding of the immunological binding partner to the peptide fragments in the sample is then determined, making the assay predictive of cardiovascular disease events.

Career Highlights

Throughout her career, Natasha Barascuk has worked with notable companies such as Nordic Bioscience A/S and Novartis AG. Her experience in these organizations has allowed her to develop and refine her innovative diagnostic methods.

Collaborations

Some of her notable coworkers include Morten A Karsdal and Sanne S Veidal. Their collaboration has contributed to the advancement of research in the field of diagnostics.

Conclusion

Natasha Barascuk's work exemplifies the intersection of innovation and healthcare. Her patents in pathology and cardiovascular diagnostics are paving the way for improved diagnostic methods and patient outcomes.