Company Filing History:
Years Active: 1993-2006
Title: The Innovative Contributions of Naomi L. Esmon
Introduction
Naomi L. Esmon is a prominent inventor based in Oklahoma City, OK (US). She has made significant contributions to the field of medical research, particularly in the area of thrombotic risk assessment and anticoagulant development. With a total of 4 patents to her name, her work has the potential to impact patient care and treatment options significantly.
Latest Patents
One of her latest patents is focused on thrombotic episode risk assays using oxidized phospholipids. This innovative assay assesses thrombotic risk by utilizing oxidized lipids comprising phospholipids as a membrane source in a clotting assay. The results are compared to an assay using unoxidized phospholipid as a membrane source, both in the presence and absence of activated protein C (APC). This assay can monitor for the presence of antibodies in patients that interfere with the anticoagulant function of APC, indicating the patient's propensity to experience episodes of vein or arterial thrombosis.
Another notable patent involves thrombin binding polypeptides. These small, buffer-soluble polypeptides have amino acid structures corresponding to specific residues of thrombomodulin and functionally equivalent analogs. They inhibit the clotting activity of thrombin and increase protein C activation. When coated onto surfaces that contact mammalian blood, these polypeptides render the surface non-thrombogenic. In pharmaceutical compositions, they act as a natural anticoagulant.
Career Highlights
Naomi has worked with esteemed organizations such as the Oklahoma Medical Research Foundation and the University of Illinois. Her research and innovations have garnered attention and respect within the scientific community.
Collaborations
Naomi has collaborated with notable individuals in her field, including Charles T. Esmon and Deborah J. Stearns. These collaborations have further enhanced her research and contributions to medical science.
Conclusion
Naomi L. Esmon's innovative work in thrombotic risk assessment and anticoagulant development showcases her dedication to improving patient outcomes. Her patents reflect her commitment to advancing medical research and her significant impact on the field.