The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 14, 2006

Filed:

Sep. 26, 2000
Applicants:

Naomi L. Esmon, Oklahoma City, OK (US);

Omid Safa Jamilabadi, Oklahoma City, OK (US);

Inventors:

Naomi L. Esmon, Oklahoma City, OK (US);

Omid Safa Jamilabadi, Oklahoma City, OK (US);

Assignee:

Oklahoma Medical Research Foundation, Oklahoma City, OK (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/56 (2006.01); G01N 33/86 (2006.01); G01N 33/92 (2006.01);
U.S. Cl.
CPC ...
Abstract

An assay to assess thrombotic risk in which oxidized lipids comprising phospholipids are utilized as a membrane source in a clotting assay and the results compared to an assay in which unoxidized phospholipid is used as a membrane source in the presence and absence of activated protein C ('APC'). The assay can monitor for the presence of antibodies in the patient which interfere specifically with the anticoagulant function of APC in an oxidation dependent or independent manner. This can indicate the propensity of the patient to experience episodes of vein thrombosis or arterial thrombosis.


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