Company Filing History:
Years Active: 1988-1993
Title: Nandini Katre: Innovator in Biological Conjugation and Protein Engineering
Introduction
Nandini Katre, an accomplished inventor based in El Cerrito, California, has made significant contributions to the field of protein engineering, with a portfolio of nine patents to her name. Her work focuses on innovative technologies that enhance biological functions through advanced conjugation techniques.
Latest Patents
One of Nandini's most notable patents involves the development of interleukin-2 muteins and their conjugation with polymers. This invention highlights the preparation of muteins of IL-2, where one of the amino acids in its native sequence is substituted with a cysteine residue. These muteins are conjugated to polyethylene glycol homopolymers or polyoxyethylated polyols through the replaced cysteine. The assembly of these muteins is achieved via host expression of mutant genes, which are modified through site-directed mutagenesis. Furthermore, her approach allows for the conjugation of other species of IL-2 at position 125, aiding in maintaining their biological activity.
Career Highlights
Throughout her professional journey, Nandini has worked with esteemed organizations, including Cetus Corporation and Cetus Oncology Corporation. Her involvement in these companies has propelled advancements in biotechnological research and development, particularly in understanding and enhancing the workings of interleukin-2.
Collaborations
Nandini Katre has had the opportunity to collaborate with many prominent professionals in her field. Notable coworkers include Michael J. Knauf and Robert J. Goodson, with whom she has worked closely to explore various applications of her research in protein conjugation.
Conclusion
Nandini Katre's innovative spirit and commitment to biological research have led her to achieve a remarkable career marked by nine patents. Her pioneering work involving the conjugation of interleukin-2 muteins with polymers showcases her role as a leading inventor in biotechnology. As her innovations continue to unfold, they promise to have a lasting impact on scientific research and therapeutic advancements.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.