The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 18, 1992
Filed:
Sep. 29, 1989
Applicant:
Inventors:
Danute E Nitecki, Berkeley, CA (US);
Nandini Katre, El Cerrito, CA (US);
Robert J Goodson, Albany, CA (US);
Lois Aldwin, San Mateo, CA (US);
Assignee:
Cetus Corporation, Emeryville, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ;
U.S. Cl.
CPC ...
424 852 ; 424 851 ; 530402 ; 530409 ; 530351 ; 514-2 ;
Abstract
The present invention is a process for preparing a pharmaceutical composition comprising a biologically active conjugated protein. It comprises a polyethylene glycol or a polyoxyethylated polyol conjugated to IL-2. This protein is conjugated to reduce its immunogenicity, and increase its solubility, and increase its circulating in vivo half-life.