Location History:
- Koekelberg, BE (1994)
- Hoeilaart, BE (1994 - 1995)
Company Filing History:
4 out of 236 
2 out of 61 
1 out of 1 Years Active: 1994-1995
Title: Nadir Mrabet - A Pioneer in Glucose Isomerase Innovations
Introduction
Nadir Mrabet, based in Hoeilaart, Belgium, is a notable inventor with a focus on enzyme technology, particularly glucose isomerases. With a total of four patents to his name, his work is significant in the field of biotechnology, contributing innovative methods for enzyme modification and application.
Latest Patents
Mrabet's latest patents include groundbreaking advancements in glucose isomerases with an altered pH optimum. His first patent discloses a method for selecting amino acid residues for replacement to create enzymes with improved pH characteristics. This method is particularly crucial for metalloenzymes, which are often inactivated at low pH due to the dissociation of metal ions. By altering the pK.a of the metal coordinating ligands or adjusting the K.ass for the metal binding, Mrabet enabled starch degradation to be successfully conducted at lower pH values. Furthermore, he provided mutant glucose isomerases exhibiting enhanced properties under application conditions. These mutant enzymes, derived from the Actinoplanes missouriensis glucose isomerase, differ from the wild-type by at least one amino acid in their sequence, showcasing the potential for improved performance in real-world applications.
Career Highlights
Throughout his career, Nadir Mrabet has contributed significantly to companies such as Gist-Brocades N.V. and Plant Genetic Systems N.V. His work in these organizations has facilitated advancements in biotechnological applications and enzyme engineering, solidifying his role as an influential figure in the field.
Collaborations
Mrabet has also collaborated with esteemed colleagues like Ignace Lasters and Wilhelmus J. Quax. These partnerships have further enriched his research efforts and have led to collaborative innovations in enzyme technology.
Conclusion
In conclusion, Nadir Mrabet's work in glucose isomerases represents a significant stride in biotechnological innovation. With his four patents and collaborative efforts, he continues to influence the development of enzyme applications, demonstrating the impact of innovative thinking in scientific research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.