Mohammad Aghaamoo

Title: Innovations by Mohammad Aghaamoo in Microfluidics and Cell Transfection

Introduction

Mohammad Aghaamoo is a prominent inventor based in Irvine, California, recognized for his groundbreaking contributions in microfluidics and cell transfection technologies. With a total of two patents, his work significantly advances the fields of single-cell genomics and proteomics.

Latest Patents

Aghaamoo's latest patents include:

1. **High-efficiency particle encapsulation in droplets with particle spacing and downstream droplet sorting**: This invention describes a passive, hydrodynamic technique utilizing a microfluidic device for co-encapsulating samples in droplets while also sorting those droplets. The method employs laminar flows and high shear liquid-liquid interfaces at a microfluidic junction, achieving an encapsulation efficiency of about 80%. This advancement holds promising implications for droplet sequencing applications.

2. **Lateral cavity acoustic transducer (LCAT) for shear-induced cell transfection**: This invention introduces the use of lateral cavity acoustic transducers (LCATs) to induce mechanical stimuli on cells. By leveraging acoustic microstreaming vortices, this technology can trap cells and administer tunable shear-induced deformations. The portable and automated device promises to enhance high-throughput cell transfection processes.

Career Highlights

Aghaamoo currently works at the University of California, where he collaborates with other distinguished researchers in his field. His innovative studies not only focus on theoretical frameworks but also strive for practical applications that can be integrated into existing biological and medical frameworks.

Collaborations

Mohammad Aghaamoo has worked alongside notable colleagues, including Abraham Phillip Lee and Xuan Li. Their combined expertise contributes to the cutting edge of research and development, fostering an environment rich in innovation and technological advancement.

Conclusion

Mohammad Aghaamoo continues to be a vital player in the realms of microfluidics and cell transfection, pushing the boundaries of scientific discovery. With his innovative approaches and patent achievements, Aghaamoo is set to make enduring impacts in his field, enhancing our understanding and capabilities in genomics and proteomics.