Rockville, MD, United States of America

Mingjun Huang

USPTO Granted Patents = 6 

 

Average Co-Inventor Count = 3.5

ph-index = 2

Forward Citations = 6(Granted Patents)


Location History:

  • Potomac, MD (US) (2008 - 2011)
  • Rockville, MD (US) (2004 - 2024)

Company Filing History:


Years Active: 2004-2025

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6 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Mingjun Huang

Introduction

Mingjun Huang is a notable inventor based in Rockville, MD (US), recognized for his significant contributions to the field of pharmaceuticals. He holds a total of 6 patents, showcasing his dedication to advancing medical treatments and therapies.

Latest Patents

Huang's latest patents include groundbreaking work on targeted dosing for the treatment of complement-mediated disorders. The dosages and methods described provide desirable pharmacokinetic (PK) and pharmacodynamics (PD) characteristics that inhibit alternative pathway complement activity. Specifically, his research indicates that at dosages ranging from about 120 mg to 200 mg BID, it is possible to achieve at least 85% inhibition of AP activity in vivo, with a plasma level of at least about 65 ng/ml. This level of inhibition is crucial for reducing the risk of complement breakthrough. Additionally, the dosage form he developed offers a significantly low C, providing an additional safety margin and better dosing flexibility.

Another significant patent involves therapeutic regimens for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). This patent outlines methods for treating subjects with PNH by administering a therapeutically effective amount of complement component C5 (C5) inhibitor, complement component C3 (C3) inhibitor, or complement factor B (CFB) inhibitor. These can be combined with a therapeutically effective amount of small molecule complement factor D (CFD) inhibitor, enhancing treatment efficacy.

Career Highlights

Throughout his career, Mingjun Huang has worked with various companies, including Achillion Pharmaceuticals, Inc. His experience in the pharmaceutical industry has allowed him to develop innovative solutions that address complex medical challenges.

Collaborations

Huang has collaborated with notable professionals in his field, including James A. Turpin and Yongsheng Song. These collaborations have contributed to the advancement of his research and the successful development of his patents.

Conclusion

Mingjun Huang's contributions to the field of pharmaceuticals through his innovative patents demonstrate his commitment to improving medical treatments. His work continues to influence the industry and offers hope for patients with complement-mediated disorders.

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