The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7985541 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 26, 2011

Filed:

Mar. 23, 2005
Applicants:

Mingjun Huang, Potomac, MD (US);

Yongnian Sun, Hamden, CT (US);

Wengang Yang, Madison, CT (US);

Inventors:

Mingjun Huang, Potomac, MD (US);

Yongnian Sun, Hamden, CT (US);

Wengang Yang, Madison, CT (US);

Assignee:

Achillion Pharmaceuticals, Inc., New Haven, CT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods for detecting populations of newly synthesized and newly initiated RNAs in a cell-free system are described. Suitable templates for the populations of newly synthesized and newly initiated RNAs are viral replicon RNAs, particularly HCV viral replicon RNA. The newly synthesized and newly initiated RNAs may be formed in the presence of a labeled nucleotide analog suitable for detection and/or quantitation of the RNAs. The assay may be employed to identify small molecule inhibitors of RNA synthesis of positive strand RNA viruses such as Hepatitis C Virus.


Find Patent Forward Citations

Huang, Mingjun. (2011). Quantitative assay for detection of newly synthesized rna in a cell-free system and identification of rna synthesis inhibitors (U.S. Patent No. 7985541). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7985541

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