The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 03, 2024
Filed:
Dec. 02, 2019
Applicant:
Achillion Pharmaceuticals, Inc., Blue Bell, PA (US);
Inventors:
Mingjun Huang, Rockville, MD (US);
Dharaben Patel, Orange, CT (US);
Steven D. Podos, New Haven, CT (US);
Assignee:
Achillion Pharmaceuticals, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61P 7/00 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 39/3955 (2013.01); A61P 7/00 (2018.01); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01);
Abstract
Provided herein are methods for treating a subject with PNH comprising administering to a subject a therapeutically effective amount of complement component C5 (C5) inhibitor, complement component C3 (C3) inhibitor, or complement factor B (CFB) inhibitor in combination with a therapeutically effective amount of small molecule complement factor D (CFD) inhibitor of Formula I or Formula II, or a pharmaceutically acceptable salt thereof.