Location History:
- Newbury Park, CA (US) (2001 - 2013)
- Tainan, TW (2006 - 2023)
Company Filing History:
20 out of 622 
11 out of 1,976 
3 out of 3 Years Active: 2001-2025
Title: Innovations and Contributions of Ming-Shi Chang in Patent Development
Introduction: Ming-Shi Chang, an accomplished inventor based in Tainan, Taiwan, has made significant strides in the field of medical research and therapy. With a remarkable portfolio of 35 patents, he has established himself as a leading figure in developing innovative treatments, particularly through the use of IL-20 antagonists.
Latest Patents: Among his latest contributions, Chang's patents include "Combination therapy using an IL-20 antagonist and an immune checkpoint inhibitor." This work offers methods and compositions that leverage the synergy between IL-20 antagonists and immune checkpoint inhibitors for enhanced treatment efficacy. Additionally, he has developed therapeutic methods aimed at "Using IL-20 antagonists for treating eye diseases." These methods are particularly focused on managing conditions such as dry eye disease (DED) and age-related macular degeneration (AMD) by blocking the signaling pathways mediated by IL-20, with the usage of antibodies that bind IL-20 or its receptor.
Career Highlights: Ming-Shi Chang has held pivotal positions at renowned institutions such as National Cheng Kung University, where he actively contributes to research and innovation in medicine and therapeutic techniques. His association with Amgen Inc. further underscores his expertise and dedication to advancing healthcare solutions through inventive methodologies.
Collaborations: Throughout his career, Chang has collaborated with notable professionals in the field, including William James Boyle and David L. Lacey. These partnerships reflect his commitment to collective research efforts aimed at addressing complex medical challenges.
Conclusion: Ming-Shi Chang's contributions to the field of inventions and patents are commendable, featuring a blend of innovative therapies and collaborative research. His ongoing commitment to improving treatments through his patented inventions continues to impact the medical community positively, paving the way for future advancements in healthcare.