The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2015
Filed:
Apr. 15, 2011
Applicant:
Ming-shi Chang, Tainan, TW;
Inventor:
Ming-Shi Chang, Tainan, TW;
Assignee:
National Cheng Kung University, Tainan, TW;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 31/7088 (2006.01); A01K 67/027 (2006.01); C07K 14/715 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); A01K 67/0276 (2013.01); A61K 31/7088 (2013.01); C07K 14/7155 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/035 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01);
Abstract
Treating a disorder (e.g., osteoporosis, renal failure, or diabetic nephropathy) associated with a signaling pathway mediated by IL-20 receptor with an agent that suppresses IL-20 receptor activity, e.g., an antibody that neutralizes IL-20 receptor via binding to IL-20R1, an antisense nucleic acid that suppresses expression of IL-20R1, a small molecule that inhibits IL-20 receptor activity, or a dominant negative mutant of IL-19, IL-20, or IL-24.