Mikhail G Shapiro

USPTO Granted Patents = 25 (Patent Applications = 20)

EPO Patents = 1

Average Co-Inventor Count = 3.9

ph-index = 5

Forward Citations = 62(Granted Patents)

Location History:

Los Angeles, CA (US) (2018 - 2024)
Pasadena, CA (US) (2022 - 2024)

Company Filing History:

25 out of 4,550

California Institute of Technology

patents

1 out of 38

Inserm (institut National De La Sante Et De La Recherche Medicale)

patents

1 out of 5,081

Centre National De La Recherche Scientifique

patents

4. 1 out of 77

Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris

patents

where one patent can have more than one assignee

Years Active: 2018-2025

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25 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12370272 - Gas-filled structures and related compositions, methods and systems to image a target site (2025-07-29),

2. 12359208 - Thermal control of T-cell immunotherapy through molecular and physical actuation (2025-07-15),

3. 12318315 - Decoding movement intention using ultrasound neuroimaging (2025-06-03),

4. 12241069 - Gas vesicle expression systems, gas vesicle constructs and related genetic circuits, vectors, mammalian cells, hosts, compositions, methods and systems (2025-03-04),

5. 12209268 - Genetically engineered gas vesicle gene clusters, genetic circuits, vectors, prokaryotic cells, compositions, methods and systems for contrast-enhanced imaging (2025-01-28),

6. 12109440 - Compositions, methods and systems for gas vesicle based cavitation (2024-10-08),

7. 11965001 - Modular dimerization thermoswitches and related monomers, dimers, constructs, dimeric complexes, vectors, cells, surfaces, devices compositions, methods and systems (2024-04-23),

8. 11959127 - Thermal bioswitches and related genetic circuits, vectors, cells, compositions, methods and systems (2024-04-16),

9. 11944423 - In-vivo monitoring of an internal volume of a mammal using magnetic field gradients (2024-04-02),

10. 11903595 - Surgical alignment by magnetic field gradient localization (2024-02-20),

11. 11786218 - Burst ultrasound reconstruction with signal templates and related methods and systems (2023-10-17),

12. 11761008 - Gas vesicle expression systems, gas vesicle constructs and related genetic circuits, vectors, mammalian cells, hosts, compositions, methods and systems (2023-09-19),

13. 11504438 - Gas-filled structures and related compositions, methods and systems to image a target site (2022-11-22),

14. 11457835 - Electromagnet gradient coil apparatus for micro-device localization (2022-10-04),

15. 11446523 - Compositions, methods and systems for gas vesicle based cavitation (2022-09-20),

Title: Mikhail G. Shapiro: A Leader in Gas Vesicle Research

Introduction: Mikhail G. Shapiro is a prominent inventor based in Los Angeles, CA, renowned for his contributions to the field of biotechnology. With an impressive portfolio of 22 patents, he has made significant advancements in the development of gas vesicle expression systems. His innovative work has the potential to revolutionize imaging techniques in biological research.

Latest Patents: Among Dr. Shapiro’s latest patents are methods and systems related to genetically engineered gas vesicle expression systems (GVES). These systems are configured to express gas vesicles in mammalian cells. The technology includes relevant gas vesicle polynucleotide constructs, reporting genetic circuits, and vectors that can be utilized in conjunction with contrast-enhanced imaging techniques. This application serves to detect and report biological events in target mammalian cells and organisms. Furthermore, he has developed hybrid gas vesicle gene clusters (GVGC) that are configured for expression in prokaryotic hosts, integrating assembly genes and structural genes from different prokaryotic species, enhancing the production of gas vesicles and potentially improving imaging processes.

Career Highlights: Mikhail G. Shapiro is affiliated with the California Institute of Technology, where he has conducted groundbreaking research in his field. His inventive efforts have garnered him 22 patents, reflecting his dedication to advancing scientific understanding and application of gas vesicles in imaging and biological detection.

Collaborations: Dr. Shapiro collaborates with esteemed colleagues such as Arash Farhadi and Azita Emami. Together, they work on pioneering projects that merge their expertise in biology and engineering to further the capabilities of gas vesicle technology.

Conclusion: Mikhail G. Shapiro's innovative contributions to the field of biotechnology, particularly in gas vesicle research, highlight his role as a leading inventor. His work not only advances scientific knowledge but also holds great promise for practical applications in medical imaging and diagnostics. As he continues to innovate, the impact of his research will likely be felt for years to come.

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