The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2025

Filed:

May. 31, 2021
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Raymond W. Bourdeau, Watertown, MA (US);

Anupama Lakshmanan, Pasadena, CA (US);

Arash Farhadi, Pasadena, CA (US);

Mikhail G. Shapiro, Los Angeles, CA (US);

Audrey Lee-Gosselin, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/75 (2006.01); A61K 49/18 (2006.01); A61K 49/22 (2006.01); C07K 14/195 (2006.01); C07K 14/32 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01); C12Q 1/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/10 (2013.01); A61K 49/1896 (2013.01); A61K 49/223 (2013.01); C07K 14/195 (2013.01); C07K 14/32 (2013.01); C12N 15/70 (2013.01); C12N 15/74 (2013.01); C12N 15/75 (2013.01);
Abstract

Hybrid gas vesicle gene cluster (GVGC) configured for expression in a prokaryotic host are described comprising gas vesicle assembly (GVA) genes native to a GVA prokaryotic species and capable of being expressed in a functional form in the prokaryotic host, and one or more gas vesicle structural (GVS) genes native to one or more GVS prokaryotic species, at least one of the one or more GVS prokaryotic species different from the GVA prokaryotic species, and related gas vesicle reporting (GVR) genetic circuits, genetic, vectors, engineered cells, and related compositions methods and systems to produce GVs, hybrid GVGC and/or image a target site.


Find Patent Forward Citations

Loading…