Michelangelo Scalone

This inventor holds 54 USPTO granted patents and 15 published patent applications, plus 14 CIPO patents and 14 EPO patents, primarily in Chiral Compound Synthesis (CPC class C07D). Top assignees: Hoffmann-La Roche Inc., Roche Colorado Corporation, Genentech, Inc.. Active years: 1992-2021.

USPTO Granted Patents = 54 (Patent Applications = 15)

% Patents Active = 57.4

CIPO Patents = 14 (Patent Applications = 4)

EPO Patents = 14 (Patent Applications = 19)

Average Co-Inventor Count = 2.9

ph-index = 6

Forward Citations = 147(Granted Patents)

Forward Citations (Not Self Cited) = 139(Dec 10, 2025)

Inventors with similar research interests:

Location History:

Baslerstrasse, CH (2010)
Birsfelden, CH (1992 - 2020)
Basel, CH (2021)

Company Filing History:

37 out of 5,011

Hoffmann-La Roche Inc.

patents

5 out of 18

Roche Colorado Corporation

where one patent can have more than one assignee

Years Active: 1992-2021

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Areas of Expertise:

Chiral Metal Complex

Pyrimidinylcyclopentane

Dihydroquinoline Derivatives

Metathesis Catalysts

Ruthenium Complexes

Heterobicyclic Amides

Phosphine Ligands

Thiazolidinedione Derivatives

Insulin Sensitizers

Epothilone Derivatives

Vinylating Pyrimidines

Asymmetric Synthesis

54 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11124532 - Chiral metal complex compounds (2021-09-21),

2. 10858324 - Processes for the preparation of pyrimidinylcyclopentane compounds (2020-12-08),

3. 10435378 - Processes for the preparation of pyrimidinylcyclopentane compounds (2019-10-08),

4. 10329288 - Process for preparing a compound (2019-06-25),

5. 9862689 - Processes for the preparation of pyrimidinylcyclopentane compounds (2018-01-09),

6. 9603816 - Process (2017-03-28),

7. 9562009 - Process to manufacture N-[(3S)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide (2017-02-07),

8. 9353081 - Bicyclic dihydroquinoline-2-one derivatives (2016-05-31),

9. 8975438 - Process for the preparation of cyclohexanecarboxylic acid derivatives (2015-03-10),

10. 8664403 - Process (2014-03-04),

11. 8450496 - Process for the preparation of propionic acid derivatives (2013-05-28),

12. 8288534 - Process for the preparation a ruthenium complex (2012-10-16),

13. 8106187 - Process for the preparation of a macrocycle (2012-01-31),

14. 7939668 - Ruthenium complexes as catalysts for metathesis reactions (2011-05-10),

15. 7910728 - Process for the preparation of a macrocycle (2011-03-22),

Title: Michelangelo Scalone: Innovator in Chiral Metal Complex Compounds

Introduction

Michelangelo Scalone, based in Birsfelden, Switzerland, is a distinguished inventor with an impressive portfolio of 54 patents. His innovative work primarily focuses on the field of chiral metal complex compounds, contributing significantly to advancements in asymmetric synthesis.

Latest Patents

Among his latest patents, Michelangelo has developed novel chiral metal complex compounds that can be utilized in asymmetric reactions, particularly in the reduction of ketones, imines, or oximes. These compounds are characterized by a unique formula involving metal (M), phosphine (PR), and other related groups (R), which have been outlined in his detailed descriptions. Another significant invention involves a process for preparing pyrimidinylcyclopentane compounds, described by a specific formula that enhances the production efficiency of these essential chemicals.

Career Highlights

Michelangelo Scalone's professional journey includes key roles in prestigious organizations such as Hoffmann-La Roche Inc. and Roche Colorado Corporation. His work at these institutions has allowed him to refine his expertise in medicinal chemistry and the development of novel compounds.

Collaborations

During his career, Michelangelo has had the pleasure of collaborating with esteemed colleagues like Kurt Puentener and Ulrich Zutter. These partnerships have fostered an environment of innovation and shared knowledge, leading to significant breakthroughs in their respective fields.

Conclusion

Michelangelo Scalone stands out as an influential figure in the realm of chemical inventions, demonstrating a remarkable ability to create and refine complex compounds that hold great promise for future applications. His contributions continue to inspire advancements in both academia and industry.