The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 2017
Filed:
Apr. 27, 2016
Process to manufacture n-[(3s)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Olaf Grassmann, Loerrach, DE;
Stefan Hildbrand, Gelterkinden, CH;
Roland Meier, Ueken, CH;
Michelangelo Scalone, Birsfelden, CH;
Urs Schwitter, Reinach BL, CH;
Beat Wirz, Reinach BL, CH;
Ulrich Zutter, Basel, CH;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/273 (2006.01); C07C 237/22 (2006.01);
U.S. Cl.
CPC ...
C07D 207/273 (2013.01); C07C 237/22 (2013.01); C07B 2200/13 (2013.01);
Abstract
The present invention provides processes to manufacture crystalline N-[(3S)-1-[4-[(3-fluorophenyl)methoxy]phenyl]-5-oxo-pyrrolidin-3-yl]acetamide. Also disclosed are compounds useful as intermediates in the methods of the invention.