Michael W Salter

Title: Michael W. Salter: Innovator in Pain Treatment and Neurological Research

Introduction

Michael W. Salter is a prominent inventor based in Toronto, Canada, renowned for his significant contributions to the field of pain management and neurological research. He holds an impressive portfolio of 11 patents, showcasing his commitment to innovation in medical science.

Latest Patents

Among his most recent patents is a groundbreaking method for treating pain which provides a novel agent helpful in alleviating pain. This agent primarily consists of a portion of the retroviral Tat protein, specifically the peptide Tat-NR2B9c. This peptide has been effectively described for its capability to inhibit the harmful effects associated with strokes and similar conditions by impeding PSD95 interactions with NMDA receptors and/or Nitric Oxide Synthases (NOS). Notably, the application showcases that the Tat-NR2B9c peptide can alleviate pain at doses lower than those required to inhibit PSD-95 interactions, presenting a significant advancement in therapeutic methods.

Another recent patent entails methods for treating stroke without the side effects typically associated with inhibiting N-type calcium channels. This invention introduces a chimeric peptide that combines an active peptide with an internalization peptide, a tat variant that facilitates cell uptake without substantially interacting with N-type calcium channels. This innovative approach allows for the treatment of stroke while minimizing adverse side effects, and the tat variant peptides can be linked to other active agents for treating a variety of diseases.

Career Highlights

Michael has collaborated with distinguished organizations such as The Hospital for Sick Children and Nono Inc., where he has advanced his research and innovations in pain treatment and neurological health. His tenure at these institutions reflects his dedication and expertise in the medical research community.

Collaborations

Throughout his career, Michael has partnered with notable colleagues including Michael P. Belmares and Jonathan David Garman. Together, they have worked to push the boundaries of medical research and create impactful solutions for patients suffering from pain and neurological disorders.

Conclusion

Michael W. Salter is a leading inventor whose innovative work in pain treatment and neurological research is paving the way for new therapeutic methods. His extensive patent portfolio signifies his influence in the field and dedication to enhancing the quality of healthcare through science and innovation.