Michael S Fleming

Title: Innovative Mind: The Contributions of Michael S. Fleming

Introduction

Michael S. Fleming, an accomplished inventor based in Londonderry, NH, has made significant strides in the world of medical innovations. With a portfolio encompassing seven patents, his work focuses on advancing immunoconjugate formulations and drug conjugate compositions that hold promise for therapeutic applications.

Latest Patents

Fleming's latest patents demonstrate his commitment to pushing the bounds of drug formulation. His immunoconjugate formulations are designed to be substantially free of particles and aggregates, providing an optimized buffered aqueous solution with a pH range of 4.5 to 7.6. These formulations include a combination of excipients such as sucrose, polysorbate 20, and histidine, among others. Additionally, his drug conjugate composition patent describes a lyophilized formulation that comprises an antibody chemically linked to a maytansinoid, aimed at effectively killing targeted cells when administered.

Career Highlights

Throughout his career, Michael S. Fleming has been associated with notable organizations such as Immunogen, Inc. and Tufts University. His work has significantly impacted the field of targeted therapies, particularly in designing formulations that enhance drug efficacy while minimizing side effects.

Collaborations

Fleming has collaborated with esteemed colleagues including Godfrey W. Amphlett and Wei Zhang. These partnerships have facilitated the development of innovative therapeutic solutions and reinforced his standing in the field of pharmaceutical research and development.

Conclusion

Michael S. Fleming's contributions to the world of inventions and innovation are both commendable and impactful. Through his ongoing research and collaboration, he continues to pave the way for advancements in medical treatments, showcasing the transformative power of targeted drug therapies.