The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 07, 2009
Filed:
Sep. 14, 2006
Applicants:
Godfrey Amphlett, Cambridge, MA (US);
Wei Zhang, Cambridge, MA (US);
Michael Fleming, Londonderry, NH (US);
Inventors:
Godfrey Amphlett, Cambridge, MA (US);
Wei Zhang, Cambridge, MA (US);
Michael Fleming, Londonderry, NH (US);
Assignee:
ImmunoGen, Inc., Waltham, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 39/44 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides a liquid composition and a lyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.