Company Filing History:
2 out of 37 
1 out of 46 
1 out of 2 Years Active: 2001-2009
Title: **Michael J. LaBarre: Innovator in Antibody Engineering**
Introduction
Michael J. LaBarre is an accomplished inventor based in San Diego, California, known for his significant contributions to the field of antibody engineering. With a total of four patents to his name, LaBarre has developed innovative methods that enhance the efficacy and application of therapeutic antibodies in medical research and treatment.
Latest Patents
Among his latest innovations are two noteworthy patents:
1. **Radiolabeling Method** - This invention focuses on antibody binding assays and radiolabeling kits. The kits are specifically designed for the radiolabeling and testing of therapeutic antibodies in commercial settings. Notably, these kits facilitate the creation and evaluation of radiolabeled anti-CD20 conjugates, which are instrumental in the treatment and imaging of B cell lymphoma tumors. All reagents in the kits are sterile, ensuring a high level of antibody radiolabeling and product stability, yielding highly reproducible results.
2. **Production of Tetravalent Antibodies** - This patent outlines a novel process for preparing biologically active antibody dimers. These dimers can be either homodimers, consisting of two identical antibody molecules linked by various bonds, or heterodimers, which include two different antibody molecules binding to distinct antigens. This innovation is crucial for inducing hyper-cross-linking of membrane antigens and holds therapeutic potential for treating diseases like cancer and autoimmune disorders.
Career Highlights
LaBarre has had an impressive career, working with leading pharmaceutical companies such as Idec Pharmaceuticals Corporation and Biogen Idec, Inc. His work has profoundly impacted the development of antibody-based therapies, particularly in oncology.
Collaborations
Throughout his career, LaBarre has collaborated with esteemed colleagues, including Paul Chinn and Gary R. Braslawsky. These collaborations have fostered an environment of innovation and advancement in the field of antibody research and development.
Conclusion
Michael J. LaBarre's pioneering work in antibody engineering demonstrates his commitment to enhancing therapeutic approaches in medicine. With his innovative patents and valuable collaborations, LaBarre continues to contribute significantly to the advancement of medical science. His contributions are especially vital in the ongoing fight against cancers and autoimmune diseases, showcasing the importance of continued research and innovation in the field.