Company Filing History:
6 out of 3,435 
5 out of 5,444 
2 out of 1,215 
Years Active: 1990-2018
Title: **Innovations by Michael I. Lerman in Tumor Suppressor Gene Research**
Introduction
Michael I. Lerman, an accomplished inventor based in Rockville, MD, has made significant contributions to the field of cancer research through his innovative patents. With a total of 10 patents to his name, Lerman has focused primarily on the role of tumor suppressor genes in the pathogenesis of human lung cancer and other malignancies.
Latest Patents
Among Lerman's latest patents is a groundbreaking study on the genes located at chromosome 3p21.3, which are identified as tumor suppressors. His research highlights how these genes play a critical role in the development of lung cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines indicate that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are involved in approximately 90% of small cell lung cancers and over 50% of non-small cell lung cancers. Additionally, he has located and isolated several recessive oncogenes at 3p21.3, including Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3, and Beta* (BLU), all defined by their homozygous deletions in lung cancers.
Career Highlights
Lerman’s career has been marked by his progressive research, which intertwines molecular biology and genetic studies to address critical health challenges. His work has not only expanded the scientific understanding of cancer biology but also has practical implications in developing therapeutic interventions for lung cancer patients.
Collaborations
Throughout his career, Michael I. Lerman has collaborated with esteemed researchers in the field, such as John Dorrance Minna and Farida Latif. These collaborations have fostered an environment of innovation and shared knowledge that has propelled advancements within cancer research.
Conclusion
As an inventor with a diverse portfolio of patents, Michael I. Lerman stands out for his impactful contributions to the understanding of tumor suppressor genes. His ongoing efforts highlight the importance of innovation in the medical field, particularly in the pursuit of effective cancer treatments.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.