The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 24, 2010

Filed:

Oct. 31, 2002
Applicants:

John Minna, Dallas, TX (US);

Yoshio Tomizawa, Takasaki, JP;

Yoshitaka Sekido, Nagoya, JP;

Michael Lerman, Rockville, MD (US);

Inventors:

John Minna, Dallas, TX (US);

Yoshio Tomizawa, Takasaki, JP;

Yoshitaka Sekido, Nagoya, JP;

Michael Lerman, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention identifies the semaphorin polypeptide SEMA3B as a tumor suppressor. This molecule can inhibit tumor growth and induce apoptosis of tumor cells when produced internally in a cancer cell via gene transfer, or when applied extracellularly. These observations permit new methods for treatment and diagnosis of cancer.


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