This inventor holds 18 USPTO granted patents and 10 published patent applications, plus 2 CIPO patents and 11 EPO patents, primarily in Cancer Immunotherapy. Top assignees: University of Pennsylvania, Novartis Ag, The Children's Hospital of Philadelphia. Active years: 2014-2022.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- New York, NY (US) (2021)
- Philadelphia, PA (US) (2014 - 2022)
Company Filing History:



Years Active: 2014-2022
Areas of Expertise:
Title: Innovations by Michael D. Kalos in Cancer Treatment
Introduction
Michael D. Kalos, located in Philadelphia, PA, is a prominent inventor and researcher in the field of cancer treatment. With an impressive portfolio of 18 patents, he has made significant contributions to innovative therapies targeting cancer. His collaborative work with industry-leading institutions has paved the way for advancements in immunotherapy.
Latest Patents
Among his latest inventions, the first focuses on "Toxicity management for anti-tumor activity of CARs." This method aims to provide effective treatment compositions for patients suffering from cancer. It involves the use of genetically modified T cells that express a chimeric antigen receptor (CAR) which contains crucial domains for targeting and treating cancer effectively.
Another significant patent is "Effective targeting of primary human leukemia using anti-CD123 chimeric antigen receptor engineered T cells." This invention offers compositions and methods for the treatment of leukemia, including acute myeloid leukemia (AML) and B-cell acute lymphoid leukemia (B-ALL). It revolves around the administration of genetically modified T cells expressing a CAR specific to CD123, which enhances the effectiveness of leukemia treatments.
Career Highlights
Michael D. Kalos's career includes notable stints at esteemed institutions such as the University of Pennsylvania and Novartis AG. His work integrates cutting-edge research with practical applications in the medical field, particularly in cancer treatment. His contributions have been crucial in advancing therapies that improve patient outcomes.
Collaborations
Throughout his career, Kalos has collaborated with distinguished colleagues, including Carl H. June and Bruce L. Levine. These partnerships have facilitated innovative developments and the sharing of expertise, enhancing the effectiveness of their research endeavors.
Conclusion
Michael D. Kalos stands out as a significant figure in the realm of cancer research and immunotherapy. His 18 patents are a testament to his creativity and dedication to finding effective treatments for patients. Through collaboration and innovation, he continues to make strides in his field, pushing the boundaries of medical science.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile