Guangzhou, China

Menghua Xiong


Average Co-Inventor Count = 3.4

ph-index = 1


Location History:

  • Urbana, IL (US) (2021)
  • Guangzhou, CN (2022)

Company Filing History:


Years Active: 2021-2022

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2 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Menghua Xiong

Introduction

Menghua Xiong is a prominent inventor based in Guangzhou, China. He has made significant contributions to the field of antimicrobial peptides, with a focus on developing innovative solutions for bacterial infections. With a total of 2 patents, his work is paving the way for advancements in medical treatments.

Latest Patents

Menghua Xiong's latest patents include groundbreaking inventions that address the challenges of bacterial resistance. One of his notable patents is for "Conformation switchable antimicrobial peptides and methods of using the same." This invention provides a class of pH-sensitive, helix/random conformation switchable antimicrobial polypeptide (HRS-AMP) compositions. These compositions selectively kill bacteria under acidic conditions in the stomach, offering a promising alternative to currently used antibiotics with diminished bacterial resistance.

Another significant patent is for "Antimicrobial alpha-helical cationic polypeptides." This invention presents antimicrobial polypeptides (AMPs) characterized by high radial amphiphilicity. Unlike typical AMPs, these new AMPs are homo-polypeptides with a stable α-helical conformation, featuring a hydrophobic helical core and a charged exterior shell. They exhibit high antibacterial activity against both Gram-negative and Gram-positive bacteria while maintaining low hemolytic activity. This innovation provides a general platform for treating drug-resistant bacterial infections.

Career Highlights

Menghua Xiong is affiliated with the University of Illinois, where he continues to contribute to research and development in the field of antimicrobial peptides. His work is recognized for its potential impact on public health and the treatment of bacterial infections.

Collaborations

Menghua Xiong has collaborated with notable researchers, including Jianjun Cheng and Lin-Feng Chen. These collaborations enhance the scope and depth of his research, fostering innovation in the field.

Conclusion

Menghua Xiong's innovative work in antimicrobial peptides is making significant strides in addressing bacterial infections and resistance. His contributions are vital for the future of medical treatments and public health.

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