Location History:
- Putney, AU (1999 - 2001)
- Gladesville, AU (1999 - 2002)
Company Filing History:
4 out of 1,332 
2 out of 30 Years Active: 1999-2002
Title: Maxine June McCall: Innovator in Catalytic Nucleic Acids
Introduction
Maxine June McCall is a distinguished inventor based in Gladesville, Australia. She has made significant contributions to the field of biotechnology, particularly in the development of catalytic nucleic acid compounds. With a total of six patents to her name, her work has advanced the understanding and application of ribozymes and minizymes.
Latest Patents
Among her latest patents are "DNA-Armed Ribozymes and Minizymes" and "Optimized Minizymes and Miniribozymes and Uses Thereof." The first invention describes catalytic nucleic acid-based compounds capable of cleaving nucleic acid polymers both in vivo and in vitro. This includes two embodiments: compounds with a short stem that does not base pair, known as minizymes, and compounds with DNA hybridizing arms and an RNA catalytic domain and stem, referred to as DNA-armed ribozymes. These compounds may be modified in their sugar, phosphate, or base components, and methods of use and treatment are also described. The second patent focuses on improved catalytic compounds, minizymes, and miniribozymes, which can hybridize with target RNA for cleavage. These compounds can be utilized as diagnostic or therapeutic agents in both in vitro and in vivo settings.
Career Highlights
Maxine has worked with notable organizations such as the Commonwealth Scientific and Industrial Research Organisation and Gene Shears Pty. Limited. Her career reflects a commitment to advancing scientific knowledge and practical applications in biotechnology.
Collaborations
Throughout her career, Maxine has collaborated with esteemed colleagues, including Philip Hendry and Trevor John Lockett. These partnerships have contributed to her innovative research and development efforts.
Conclusion
Maxine June McCall's work in the field of catalytic nucleic acids has positioned her as a leading inventor in biotechnology. Her patents reflect her dedication to innovation and the potential for significant advancements in therapeutic applications.
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