The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2002
Filed:
Dec. 08, 1992
Applicant:
Inventors:
Philip Anthony Jennings, Chatswood West, AU;
Maxine June McCall, Gladesville, AU;
Philip Hendry, Rozelle, AU;
Assignee:
Gene Shears Pty. Limited, Neutral Bay, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 2/104 ; C12Q 1/68 ;
U.S. Cl.
CPC ...
C07H 2/104 ; C12Q 1/68 ;
Abstract
The invention describes catalytic nucleic acid based compounds capable of cleaving nucleic acid polymers both in vivo and in vitro. Two embodiments of this invention are compounds with a short stem that does not base pair, a minizyme, and compounds with DNA hybridizing arms and RNA catalytic domain and stem, DNA-armed ribozymes. The compounds of this invention, while nucleotide based may be substituted or modified in the sugar, phosphate, or base. Methods of use and methods of treatment are also described.