Company Filing History:
Years Active: 2008-2020
Title: The Innovative Contributions of Matthias Ballhause
Introduction
Matthias Ballhause is a notable inventor based in Berlin, Germany. With an impressive portfolio of 9 patents, he has made significant contributions in the field of DNA analysis and methylation detection. His groundbreaking work continues to have a profound impact on genetics research and medical diagnostics.
Latest Patents
Among Matthias Ballhause’s latest innovations is a method for determining the presence or absence of methylation in a sample. This invention relates to compositions and methods that provide DNA fragments from a remote sample, which may include blood, plasma, serum, or urine from a human individual. The process isolates DNA from the sample, enabling the differentiation between methylated and unmethylated cytosine. It includes various embodiments for methylation analysis and whole genome amplification of bisulfite treated DNA.
Additionally, he developed a method for providing DNA fragments derived from archived samples, including paraffin-embedded and fixed-tissue biopsies. This method guarantees high yields of long DNA fragments while ensuring that the isolated genomic DNA remains free from contaminants like proteins and peptides. This innovative approach is characterized by its cost-effectiveness and high reproducibility, with yields of DNA that meet or exceed 20% before amplification.
Career Highlights
Matthias Ballhause has built a remarkable career primarily at Epigenomics AG, where he has been able to translate complex genetic concepts into practical methodologies through his inventions. His work has not only advanced scientific knowledge but has also paved the way for potential applications in personalized medicine and diagnostics.
Collaborations
Throughout his career, Matthias has collaborated with several notable professionals in the field, including Kurt Berlin and Dimo Dietrich. These partnerships have helped enhance the development and application of his innovations, fostering an environment of teamwork and shared vision in pushing the boundaries of genetic research.
Conclusion
Matthias Ballhause stands out as a distinguished inventor whose contributions to the field of DNA analysis and methylation detection are both innovative and practical. His commitment to research and development continues to influence the landscape of genetics, promising significant advancements for the future. Through his patents and collaborations, he exemplifies the impact that individual creativity and expertise can have on scientific progress.