The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Apr. 17, 2006
Matthias Ballhause, Berlin, DE;
Kurt Berlin, Stahnsdorf, DE;
Theo DE Vos, Seattle, WA (US);
Dimo Dietrich, Berlin, DE;
Volker Liebenberg, Berlin, DE;
Catherine Lofton-day, Seattle, WA (US);
Joe Lograsso, Seattle, WA (US);
Jennifer Maas, Seattle, WA (US);
Fabian Model, Berlin, DE;
Matthias Schuster, Berlin, DE;
Andrew Z. Sledziewski, Shoreline, WA (US);
Reimo Tetzner, Berlin, DE;
Matthias Ballhause, Berlin, DE;
Kurt Berlin, Stahnsdorf, DE;
Theo De Vos, Seattle, WA (US);
Dimo Dietrich, Berlin, DE;
Volker Liebenberg, Berlin, DE;
Catherine Lofton-Day, Seattle, WA (US);
Joe Lograsso, Seattle, WA (US);
Jennifer Maas, Seattle, WA (US);
Fabian Model, Berlin, DE;
Matthias Schuster, Berlin, DE;
Andrew Z. Sledziewski, Shoreline, WA (US);
Reimo Tetzner, Berlin, DE;
EPIGENOMICS AG, Berlin, DE;
Abstract
Aspects of the present invention relate to compositions and methods for providing DNA fragments from a remote sample. In particular aspects a remote sample comprising DNA is provided, DNA is isolated from the remote sample, and the isolated DNA is treated in a way which allows differentiation of methylated and unmethylated cytosine. Additional, particular embodiments provide compositions and methods for methylation analysis of DNA derived from a remote sample. Other aspects provide for compositions and methods of whole genome amplification of bisulfite treated DNA. Other aspects provide methods for determining the presence or absence of methylation of at least one cytosine, or a series of cytosines in cis, in human DNA of a blood sample, a plasma sample, a serum sample or a urine sample from a human individual.