Matthew J Henry

Title: Innovations by Matthew J. Henry: Pioneering Gene Editing Techniques

Introduction

Matthew J. Henry, based in Indianapolis, IN, is a notable inventor in the field of genetic engineering with a remarkable portfolio of 14 patents. His work primarily focuses on innovative methods for gene editing and trait stacking, contributing significantly to advancements in plant genome modification.

Latest Patents

Among his latest contributions, the patent titled "FAD3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks" outlines a gene editing method that enables precise alterations in the FAD3 gene within a cell. This technique facilitates the introduction of a nucleic acid molecule linked to desired traits into the FAD3 gene, creating targeted breaks essential for genetic modification.

Another significant patent is the "Engineered Transgene Integration Platform (ETIP) for gene targeting and trait stacking." This innovative platform allows for the random or targeted insertion of elements within plant genomes, enhancing the speed of selection and detection of genes of interest (GOI). Notably, this technology employs various targeting techniques, including zinc finger nucleases and CRISPR, to create specific double-stranded breaks within the plant genomic context. The ETIP supports the development and testing of transgenic plants where the integrated DNA expresses exogenous products, such as proteins or RNA.

Career Highlights

Matthew J. Henry has made impactful contributions while working for prominent companies such as Dow Agrosciences LLC and Sangamo Therapeutics, Inc. His experience in these organizations has equipped him with extensive knowledge in the field of agricultural biotechnology and genetic innovation.

Collaborations

Throughout his career, Henry has collaborated with esteemed colleagues, including Steven Robert Webb and Noel Cogan. These partnerships have further enhanced the development of groundbreaking technologies and methodologies in gene editing and transgenic research.

Conclusion

Matthew J. Henry's inventive spirit and dedication to advancing genetic engineering solidify his reputation as a key figure in the biotechnology sector. His patents not only exemplify cutting-edge research but also herald a new era of possibilities in plant genetics, making significant strides toward agricultural innovation and sustainability.