Company Filing History:
Years Active: 2002-2011
Title: Innovations in Nucleic Acid Sequencing by Mathieu Foquet
Introduction
Mathieu Foquet is a prominent inventor based in Ithaca, NY. He has contributed significantly to the field of nucleic acid sequencing, holding a total of 10 patents. His innovative approaches have advanced the methodologies employed in analyzing nucleic acid sequences, making significant impacts on research and diagnostic applications.
Latest Patents
Foquet's latest patents include groundbreaking methods for analyzing nucleic acid sequences. One such patent details a method of sequencing a target nucleic acid, wherein a complex is formed with a polymerase enzyme, a target nucleic acid molecule, and a primer immobilized on a support. The method utilizes a fluorescent label attached to the nucleotide's terminal phosphate group, allowing for the identification of nucleotide analogs incorporated during polymerization based on their signal duration.
Another significant patent by Foquet focuses on high-speed nucleic acid sequencing. This method measures the temporal order of base additions during the polymerization reaction of nucleic acid molecules. Each labeled nucleotide is designed with an acceptor fluorophore that is removed upon incorporation into a growing strand. The emitted fluorescent signal during this process, which occurs through resonance energy transfer, allows for the deducing of the sequence as each base is added.
Career Highlights
Foquet's work at the Cornell Research Foundation Inc. has been instrumental in the development of innovative technologies in nucleic acid analysis. His commitment to advancing scientific knowledge through invention has positioned him as a leader in his field. With his ten patents, he continues to push the boundaries of molecular biology and genetic research.
Collaborations
Throughout his career, Mathieu Foquet has collaborated with notable colleagues such as Harold G. Craighead and Jonas Korlach. These partnerships have fostered a rich environment for innovative thought, promoting the evolution of cutting-edge technologies in nucleic acid sequencing.
Conclusion
Mathieu Foquet's contributions to nucleic acid sequencing reflect his dedication to innovation and excellence in research. His patents and collaborative efforts signify a commitment to advancing the scientific community's understanding and applications of molecular biology. As he continues to innovate, Foquet's work is poised to make a lasting impact on the future of genetic research and diagnostics.
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