Tsuchiura, Japan

Masao Fukagawa


Average Co-Inventor Count = 5.6

ph-index = 3

Forward Citations = 31(Granted Patents)


Company Filing History:


Years Active: 1993-1997

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5 patents (USPTO):Explore Patents

Title: **Masao Fukagawa: Innovator in Pharmaceutical Chemistry**

Introduction

Masao Fukagawa is a prominent inventor based in Tsuchiura, Japan. With a commendable portfolio of five patents, he has significantly contributed to the field of pharmaceutical chemistry, particularly in the production of cephalosporin compounds.

Latest Patents

Fukagawa's latest patents showcase his expertise in the synthesis of 7-aminocephem compounds. One notable patent outlines a process for producing these compounds or their salts through microorganisms that have been transformed with a vector containing a specific gene. This innovative approach allows for the conversion of cephalosporin compounds into the desired 7-aminocephem format. Furthermore, he developed a patented cephalosporin C acylase derived from Pseudomonas diminuta N-176, which effectively catalyzes the conversion of various cephalosporin derivatives into 7-aminocephalosporanic acid. This enzyme's unique characteristics include an alpha-subunit with a molecular weight of 26 kDa and a beta-subunit weighing 58 kDa. Additionally, he established a method for the recombinant production of this enzyme using Escherichia coli.

Career Highlights

Masao Fukagawa has made remarkable strides in his career at Fujisawa Pharmaceutical Company, Ltd., where he continues to push the boundaries of pharmaceutical innovation. His dedication to research and development has positioned him as a leader in the industry.

Collaborations

Throughout his career, Fukagawa has worked alongside talented colleagues, including Morita Iwami and Ichiro Aramori. Together, they have collaborated on various projects that leverage their combined expertise in pharmaceutical development.

Conclusion

Masao Fukagawa's contributions to the production of cephalosporin compounds demonstrate his innovative spirit and commitment to advancing pharmaceutical science. His work not only enhances our understanding of these compounds but also paves the way for new therapeutic possibilities in medicine.

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