Company Filing History:
Years Active: 2000-2004
Title: Mary Jo Donovan: Innovator in Stereoselective Processes
Introduction
Mary Jo Donovan, based in North Brunswick, NJ, is a distinguished inventor recognized for her significant contributions to the field of stereoselective processes. With a total of three patents to her name, her work primarily focuses on advancements that can aid in treating serious conditions such as Alzheimer’s disease.
Latest Patents
Among her latest innovations, two patents stand out. The first, titled "Stereoselective Reduction of Substituted Acetophenone," involves novel stereoselective processes for preparing (S)-1-arylethanols through the reduction of keto group containing compounds using microorganisms. The resulting (S)-1-arylethanols are vital intermediates in synthesizing compounds that inhibit γ-secretase, which has therapeutic implications for Alzheimer's disease.
The second patent, "Stereoselective Reductive Amination of Ketones," describes processes for the enzymatic conversion of certain keto carboxylic acid derivatives to form corresponding alkylamino acid compounds. This invention includes engineered yeast host cells that express specific recombinant nucleic acids capable of producing phenylalanine dehydrogenase and formate dehydrogenase enzymes, further enhancing the applications in biochemical synthesis.
Career Highlights
Mary Jo Donovan serves as an innovator at Bristol-Myers Squibb Company, a leading global biopharmaceutical firm. Her expertise has led to her recognition as a key figure in her field, focusing on the intersection of biotechnology and pharmaceutical development.
Collaborations
Throughout her career, Mary Jo has collaborated with esteemed coworkers Ramesh N. Patel and Steven L. Goldberg. Their combined expertise has contributed to the success of her innovative projects and the effective realization of cutting-edge research initiatives.
Conclusion
Mary Jo Donovan exemplifies the spirit of innovation and dedication in the biotech industry. Her contributions, particularly in the development of stereoselective processes, not only advance scientific understanding but also pave the way for potential new treatments for serious diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.