The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2000

Filed:

Jul. 08, 1999
Applicant:
Inventors:

Ronald Hanson, Morris Plains, NJ (US);

Mary Jo Donovan, North Brunswick, NJ (US);

Steven Goldberg, Basking Ridge, NJ (US);

Paul A Jass, Charles City, IA (US);

Wen-Sen Li, Holmdel, NJ (US);

Ramesh Patel, Bridgewater, NJ (US);

Keith Ramig, Orange, NJ (US);

Laszlo J Szarka, East Brunswick, NJ (US);

John J Venit, North Brunswick, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ;
U.S. Cl.
CPC ...
435106 ; 435108 ; 435111 ; 435113 ; 435115 ;
Abstract

Processes for stereoselective enzymatic conversion of certain keto carboxylic acid derivatives to form the corresponding alkylamino acid compounds are described. The invention also concerns an engineered yeast host cell containing recombinant nucleic acid capable of expressing a phenylalanine dehydrogenase, as well as an engineered host cell containing recombinant nucleic acid capable of expressing a phenylalanine dehydrogenase enzyme and nucleic acid capable of expressing a formate dehydrogenase enzyme.


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