Martha S Hayden

Title: Martha S Hayden: Innovator in Biopharmaceuticals

Introduction

Martha S Hayden is a prominent inventor based in Everett, WA (US). She has made significant contributions to the field of biopharmaceuticals, holding a total of 7 patents. Her work focuses on the development of innovative solutions for enhancing immune responses and producing biologically active proteins.

Latest Patents

One of her latest patents involves expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell. This invention provides an expression vector that can encode either monospecific or bispecific fusion proteins. In one embodiment, the vector encodes a monospecific fusion protein, which includes a recombinant monospecific single chain cassette with a DNA sequence that encodes a first binding domain capable of binding a cell surface antigen. In another embodiment, the vector encodes a bispecific fusion protein, comprising a recombinant bispecific single chain cassette with DNA sequences for two different binding domains, each capable of binding a distinct antigen. Additionally, she has developed modified sFv molecules that stimulate adhesion between cells, thereby enhancing the immune response against diseases. These molecules typically consist of an antigen binding site of an antibody and a portion of a transmembrane domain of a cell surface receptor.

Career Highlights

Martha has worked with notable companies in the biopharmaceutical sector, including Bristol-Myers Squibb Company and Oncogen. Her experience in these organizations has allowed her to contribute to groundbreaking research and development in her field.

Collaborations

Throughout her career, Martha has collaborated with esteemed colleagues such as Peter S Linsley and Jeffrey A Ledbetter. These partnerships have further enriched her work and expanded the impact of her inventions.

Conclusion

Martha S Hayden is a distinguished inventor whose work in biopharmaceuticals has led to significant advancements in the production of fusion proteins and immune response enhancement. Her contributions continue to influence the field and inspire future innovations.