The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2004

Filed:

Nov. 27, 1996
Applicant:
Inventors:

Jeffrey A. Ledbetter, Seattle, WA (US);

Martha Hayden, Everett, WA (US);

Perry Fell, Redmond, WA (US);

Robert Mittler, Woodinville, WA (US);

Gosta Winberg, Bromma, SE;

Assignee:

Bristol-Myers Squibb Co., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/9395 ; C07K 1/646 ; C12N 5/10 ;
U.S. Cl.
CPC ...
A61K 3/9395 ; C07K 1/646 ; C12N 5/10 ;
Abstract

The modified sFv molecules of the present invention stimulate adhesion between cells thereby enhancing the immune response against disease. These molecules generally comprise an antigen binding site of an antibody and at least a portion of a transmembrane domain of a cell surface receptor.


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