Marta Amaral

Title: Marta Amaral: Innovator in Multispecific Binding Proteins

Introduction

Marta Amaral is a distinguished inventor based in Frankfurt-am-Main, Germany. She has made significant contributions to the field of biotechnology, particularly in the development of multispecific binding proteins. Her innovative work has led to the filing of a patent that showcases her expertise and creativity in this area.

Latest Patents

Marta Amaral holds a patent for "Multispecific binding proteins with mutant fab domains." This patent describes binding proteins that comprise a VL region paired with a VH region, and a CH1 region paired with a CL region. The VL and VH regions include opposite charged mutations to facilitate pairing, while the CH1 and CL regions contain mutations to enhance pairing. Additionally, the patent covers binding proteins with engineered cysteine residues in the VH/VL pair to form disulfide bonds. The patent also includes nucleic acids encoding these binding proteins, expression vectors, host cells, pharmaceutical compositions, and methods for treatment using the described binding proteins.

Career Highlights

Marta Amaral is currently employed at Sanofi, a global healthcare company. Her role at Sanofi allows her to apply her innovative ideas and contribute to advancements in medical science. Her work is characterized by a commitment to developing novel therapeutic solutions that can improve patient outcomes.

Collaborations

Marta collaborates with notable colleagues, including Christian Beil and Ingo Focken. These partnerships enhance her research and development efforts, fostering an environment of innovation and creativity.

Conclusion

Marta Amaral is a pioneering inventor whose work in multispecific binding proteins exemplifies the intersection of science and innovation. Her contributions to biotechnology are significant and continue to influence the field.